This is something most sensible security guys always knew.
- Application white-listing
- Patching applications:
- Patching operating system vulnerabilities:
- Restricting administrative privileges to operating systems and applications based on user duties:
Check the following link for more details
http://h30499.www3.hp.com/t5/HP-Security-Products-Blog/Can-these-4-strategies-prevent-85-of-targeted-high-risk/ba-p/6744269
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