Fileless Malware is coming - Are you ready? Here are a few pointers that could help

1. Patching
2. Least Privilege (App and User)
3. Restrict PowerShell (Constraint Language Mode)
4. Blacklisting / Redirect - Site / URL
5. Behavior Monitoring(Super Users)
6. Human Error (Training )

http://www.computerweekly.com/opinion/Security-Think-Tank-How-to-tackle-fileless-malware-attacks